Divided into chapters, the film first chronicles Hemel's many sexual conquests, but then takes on a different tone as it explores her complicated relationship with her father, Gijs. A dapper auctioneer, Gijs has dated a series of younger women since Hemel's mother's death. But when Gijs starts seeing the charming Sophie, for the first time Hemel feels that her special relationship with her father is threatened...

The film is set in 1521 Antwerp, in a Europe ravaged by religious wars, and during the early years of the Reformation. It tells the story of the twelve year old, Falko Voeten – a printer’s son. When Falko’s father, Klaas Voeten, a printer of forbidden literature, is caught by the Inquisition for printing a letter written by Maarten Luther; Falko is unwittingly propelled into helping his father and into searching for the letter. Threatened by the Inquisition but aided by Marieke, a Catholic orphan girl from the underground sewers, Falko is faced with a race against time if he is to save his father from being executed for heresy.

Before he built a drug empire, Ferry Bouman returns to his hometown on a revenge mission that finds his loyalty tested — and a love that alters his life.